Cannabis is a popular recreational drug, and its active ingredient, tetrahydrocannabinol (THC), is known to cause tolerance when used regularly. THC works by affecting type 1 cannabinoid (CB) receptors in the brain. When these receptors are repeatedly activated, they become desensitized and eventually internalized, meaning that more THC is needed to achieve the same effects. Fortunately, there are ways to manage THC tolerance and restore CB receptors. The exact length of time needed to abstain from cannabis in order to restore CB receptors is not known, but research suggests that taking a break helps.
It's important to note that cannabis tolerance is unique in that it does not appear to be affected by genetic predisposition or body weight, as is the case with alcohol. Therefore, it's recommended to start with a low dose of THC, even if you're a large person. Too much THC can overwhelm the receptors and reduce their functioning. This is why it's important to be aware of how THC affects your mental state and decision-making. If you're taking a CBD-only product alongside one with THC, it's important to continue taking CBD during your break.
Abstinence from cannabis is more intense when there are fewer CB1 receptors available. In the West, where marijuana with a relatively low content of delta 9-THC is widely smoked, dependence on the drug appears to be more related to social environment than its pharmacological properties. Increasing CBD levels may also affect some of the symptoms that were previously relieved with THC products. The human body is quite resilient and flexible, so some people may need several standard doses of 10 mg of THC to feel its effects. To manage THC tolerance, it's important to take regular breaks from cannabis use and start with low doses. This will help ensure that you get the most out of your cannabis experience.